33 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential ... insipidus • Nephrogenic ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... renal mechanism 2) ... • Euvolemic: Diabetes ... #Differential # ... #sodium
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Diagnosis Algorithm - Diabetes ... history Step #2 ... Uglucose Step #3 ... #Sodium #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
water unavailable 2) ... Osmotic Diuresis ... post-obstructive 3) ... Diabetes Insipidus ... #nephrology #sodium
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
- Differential ... water loss, Serum Sodium ... administration • Osmotic diuresis ... 300 mmol/kg • Diabetes ... #Nephrology #Differential
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... - Differential ... Insensible losses Sodium ... Water Central Diabetes ... Diagnosis #Table
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Repeat the sodium ... Step 2. ... administration Step 3. ... volume loss - diuretics ... Workup #Algorithm #Nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Serum Osmolarity 2) ... Urine Osmolarity 3) ... Urine Sodium 4) ... #Differential #
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... nephrotic syndrome • Hyponatremia ... and euvolemic hyponatremia ... #Nephrology #Pharmacology ... #Medications #Table
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) ... Sodium loss from ... tubules 3) Naturiesis ... → diuresis → hypovolaemia ... #hyponatremia #