15 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
- Differential ... perspiration Renal ... concentrating defect ... insipidus • Nephrogenic ... #sodium #high
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... in Kidney Tubule ... #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
- Differential ... Insensible losses Sodium ... sensitivity in kidneys ... Eric Strong https ... Diagnosis #Table
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... mOsm/kg - Implies renal ... , Ingestion Renal ... #Differential # ... #sodium
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Hyponatremia - Differential ... Suppressed - Advanced renal ... #Differential # ... Diagnosis #Table ... #Causes #Sodium
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Differential Diagnosis ... The differential ... , Dehydration: neurologic ... Diabetes Insipidus: neurogenic ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
≥100): SIADH, Renal ... Sodium loss (diuretics ... #differential # ... diagnosis #table ... #sodium #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... nephrotic syndrome • Hyponatremia ... Tolvaptan) • Treatment ... and euvolemic hyponatremia ... #Medications #Table
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
of Polyuria - Differential ... Other: Mannitol Defect ... injury, Tumor • Nephrogenic ... DI (Renal resistance ... - Strong Medicine
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Heat injury, Heat stroke ... Hyperuricemia • Hyponatremia ... nephrotoxicity to kidney ... #nephrology