14 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... concentrating defect ... insipidus • Nephrogenic ... #Causes #nephrology ... #sodium #high
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... in Kidney Tubule ... #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Euvolemic (Low ... #Differential #Diagnosis ... Workup #Algorithm #nephrology ... #sodium
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
Hypernatremia Classification ... Gestational DI, Nephrogenic ... Classification #Features #Diagnosis ... #Comparison #Table ... #Nephrology
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
, Anaphylaxis, Neurogenic ... Disease, Mechanical Defect ... #inopressors #diagnosis ... #management #comparison ... #table
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... - Differential Diagnosis ... Insensible losses Sodium ... sensitivity in kidneys ... #Table #Causes
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... can be high or low ... #differential #diagnosis ... #table #sodium ... #nephrology
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
body water in comparison ... the hypothalamus detect ... stimulated in states of low ... collecting duct in the kidneys ... activated in states of low
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... nephrotic syndrome • Hyponatremia ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology ... #Medications #Table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
myalgia, serositis, Kidney ... in >90% - Low ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management