9 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... concentrating defect ... insipidus • Nephrogenic ... #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm ... #Differential #Diagnosis ... #Workup #Algorithm ... #nephrology #sodium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... in Kidney Tubule ... #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
, Anaphylaxis, Neurogenic ... Disease, Mechanical Defect ... pharmacology ... inopressors #diagnosis ... management #comparison #table
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... - Differential Diagnosis ... Insensible losses Sodium ... sensitivity in kidneys ... #Table #Causes
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Numerous drugs taken by elderly persons can affect water balance by direct action on the kidney
Numerous drugs taken ... action on the kidney ... (Table IV). ... #Diagnosis #Pharmacology ... #Geriatrics #Hyponatremia
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
• Symptomatic hyponatremia ... dysfunction - K+ deficits ... intoxication Initial Workup ... , Urine Sodium ... #management #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... - Toxins - Drugs ... Hyperuricemia • Hyponatremia ... nephrotoxicity to kidney ... causes #treatment #nephrology