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diagnosis nephrology differential management treatment table algorithm hyponatremia causes medications constipation criticalcare emergencies low workup acidosis adenosine antagonists anticonvulsants antimuscarinic
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Muscarinic Receptor Agonists and Antagonists Muscarinic Receptor Agonists Methacholine • Diagnosis of bronchial airway Carbachol • Glaucorna (topical
Muscarinic Receptor Agonists ... Muscarinic Receptor Agonists ... postoperative, neurogenic ... bladder, enuresis, neurogenic ... #Medications #Pharmacology
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
Causes of Hypernatremia ... insipidus • Nephrogenic ... administration #Hypernatremia ... Causes #nephrology #sodium
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... mmol/L - true hyponatremia ... • nephrotic syndrome ... renal failure #Hypernatremia
Medications Used in Hypertensive Emergencies Vasodilators: Hydralazine, Nitroglycerin, Sodium nitroprusside Calcium Channel Blockers: Clevidipine, Nicardipine ß-Blockers: Esmolol, Labetalol,
Nitroglycerin, Sodium ... Phentolamine D1 Receptor Agonists ... Management #Treatment #Pharmacology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Hyponatremia ... • Nephrogenic ... V1 receptor-agonist ... and euvolemic hyponatremia ... Diuresis #Nephrology #Pharmacology
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
Modified Hyponatremia ... Algorithm Hypertonic Hyponatremia ... irrigants Hypotonic Hyponatremia ... Cirrhosis, Nephrotic syndrome ... Algorithm #diagnosis #sodium
Hypernatremia - Differential Diagnosis and Treatment Hypernatremia is almost always due to unreplaced water loss (free water
Hypernatremia - ... and Treatment Hypernatremia ... Diabetes Insipidus: neurogenic ... , nephrogenic 4 ... management #nephrology #sodium
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
Etiologies of Hypernatremia ... Insensible losses Sodium ... congenital disorders Nephrogenic ... DrEricStrong #Hypernatremia
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
limb Gitelman syndrome ... cell epithelial sodium ... of epithelial sodium ... exchanger,H+-ATPase Nephrogenic ... -2 deficiency Nephrogenic
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