51 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... mannitol) 3) Loop diuretic ... Thiazides-type diuretics ... #pharmacology # ... nephrology #medications
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP DIURETICS ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... summary #table #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified ... Diagnosis #Algorithm #Workup
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... medications in ... Spironolactone MCW Nephrology ... MCW_Nephrology #diuretics ... #pharmacology #
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
3L /day Water Diuresis ... Insipidus Mixed Diuresis ... Failure Solute Diuresis ... Diagnosis #Algorithm #causes ... #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) Check Urine ... • Hypovolemic: Diuretics ... osmotic (solute) diuresis ... #Algorithm #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... especially thiazide diuretics ... Hypo-osmolar urine ... #Hyponatremia #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... osmolarity If cause ... #Injury #AKI #Workup ... Differential #Diagnosis #nephrology ... #causes
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Low Cl intake, Diuretics ... (late) • High Urine ... Cl-: Diuretics, ... Diagnosis #Algorithm #Nephrology ... #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... especially thiazide diuretics ... Hypo-osmolar urine ... #Hyponatremia #Nephrology