13 results
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Syndrome (APS) ... APS is a rare autoimmune ... 1 of the three aPLs ... #Syndrome #APS ... #diagnosis #management
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
in (Antiphospholipid ... Syndrome) APS ... #Syndrome #APS ... #management #EULAR2019 ... #hematology #treatment
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS
Previous Thrombosis?
Previous Pregnancy Complications?

Dr. Laurent ARNAUD @Lupusreference

#obstetrics
in (Antiphospholipid ... Syndrome) APS ... Previous Thrombosis ... #Syndrome #APS ... #guidelines #rheumatology
Pregnancy Management in Patients with SLE and/or APS - Conception to Delivery
 • Stop Teratogenic Drugs
and/or APS - Conception ... echocardiography • aPL ... +/APS - +heparin ... #SLE #APS #lupus ... #antiphospholipid
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hyperviscosity, TTP, APLS ... • Nephrotic Syndrome ... Malignancy - Antiphospholipid ... antibodies (APLS ... pathophysiology #hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... , others (RNP, aPL ... antibodies) • Antiphospholipid ... Antibody Syndrome ... LAC) • Sjogren Syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... vasculopathy, thrombosis ... (for secondary APS ... cerebritis #diagnosis #management
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... (catastrophic APS ... , SRC, SLE), cancer ... @AnnKumfer #Thrombotic ... Microangiopathy #TMAs #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... ARUPConsult @ARUPLabs #APLS ... #Antiphospholipid ... Algorithm #diagnosis #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, dural sinus thrombosis ... pathergy test (this is ... Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management