36 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... APTT Step 1: Is ... the PT or APTT ... ISNeducation #Abnormal ... #diagnosis #hematology
Prolonged APTT - Diagnostic Algorithm

#Prolonged #APTT #PTT #abnormal #Diagnosis #Algorithm #hematology
Prolonged APTT - ... Diagnostic Algorithm ... #Prolonged #APTT ... #PTT #abnormal ... #hematology
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... PT - Prolonged aPTT ... PT - Prolonged aPTT ... #Coagulation #Abnormal ... #Hematology #Diagnosis
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
an inhibitor of normal ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Prolonged PT (INR), Normal ... PTT, Normal PT ... , Normal PT (INR ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... hemosiderin • PT/aPTT ... normal • DAT ... #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Laboratory • Normal ... PT/INR • Normal ... aPTT (prolonged ... VonWillebrand #Disease #Diagnosis ... #Hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... may be normal in ... antigen (vWF:Ag) are normal ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... < 1.5 x normal ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Expected: Low (or normal ... aggregation PT, aPTT ... factors, Can be normal ... ISTH #Scoring #diagnosis ... #hematology #laboratory