27 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... #Coagulation #Abnormal ... #APTT #Laboratory ... #Hematology #Diagnosis
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Lab patterns seen ... A table of lab ... values compiled ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... Genetics #IEM #Laboratory
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Prolonged PTT, Normal ... #PPT #PT #INR #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Diagnosis Algorithm ... Destruction • Abnormal ... #Diagnosis #Algorithm ... #Causes #Hematology
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... connections and pathophysiology ... See the lab values ... #Diagnosis #Algorithm ... #Differential #
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... and Management Algorithm ... ±AKI Initial labs ... hemosiderin • PT/aPTT normal ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... venipuncture sites Laboratory ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... treatment #management #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Hypophostphatemia Laboratory ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
- Polycythemia Differential ... Diagnosis Algorithm ... Hemoglobin: • Males ... ), TEMPI (VEGF normal ... #hematology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Tests (LFTs) - Normal ... Values and Interpretation ... prothrombin time across labs ... #Tests #LFTs #Laboratory ... #diagnosis #hepatology