60 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... ±AKI Initial labs ... hemosiderin • PT/aPTT normal ... #Diagnosis #Management ... #Algorithm #hematology
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
2020 ACR-EULAR Classification ... at least 1): Normal ... CRP and normal ... diagnosis #EULAR #Classification ... #rheumatology
Mitral Valve Regurgitation - Carpentier Classification
Type I - Normal Leaflet Motion
   - Type la
Mitral Valve Regurgitation ... - Carpentier Classification ... Type I - Normal ... Motion - Type la ... #Carpentier #Classification
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
values: WBC >100k ... , + lab signs of ... values: Elevated ... TLS #diagnosis #management ... #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
1 or Type 3) — differentiate ... cytometry— GP lb ... defects of GP lb ... Platelet #disorders #hematology ... #hemepath #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Chronic Disease Normal ... #Anemia #MCV #Classification ... #Differential # ... Algorithm #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... AS, prosthetic valve ... Hemolytic #Anemia #Differential ... Diagnosis #causes #classification ... #hematology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Tests (LFTs) - Normal ... Values and Interpretation ... prothrombin time across labs ... LFTs #Laboratory #Values ... Interpretation #diagnosis #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Blood Smear ↑ abnormal ... #Hemolysis #Differential ... #Diagnosis #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Segmented Neutrophil (Normal ... ) Differential ... appreciate the value ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology