31 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... SLE • CLL • APLA ... Non-lmmune: • HELLP Syndrome ... Prosthetic Heart Valve ... #Causes #Hematology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
Behcet's disease - APLS ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology ... #differential #algorithm
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... values: WBC >100k ... , + lab signs of ... values: Elevated ... diagnosis #management #hematology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... Differential Diagnosis Algorithm ... • Budd-Chiari syndrome ... Differential #Diagnosis #Algorithm ... #Hepatology #causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Differential Diagnosis Algorithm ... Myelodysplastic Syndromes ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Diagnosis: • Labs ... 500 mg QD until normal ... diagnosis #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hyperviscosity, TTP, APLS ... • Drugs: - Oral ... • Nephrotic Syndrome ... from prosthetic valves ... pathophysiology #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Differential Diagnosis Algorithm ... Drug-induced AIHA - Abnormal ... Prosthetic heart valves ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... - PNH - APLS ... Decreased Support Of Dermal ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... old, ~10,000 new cases ... only curative treatment ... #hematology #oncology