24 results
diagnosis differential oncology rheumatology blood mds myelodysplastic product reactions thrombosis activation anemia aplastic apml arterial cardiology chf clinical coagulation common
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Non-lmmune: • HELLP Syndrome ... Prosthetic Heart Valve ... #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Algorithm Suspected ... TMA: Unexplained thrombocytopenia ... ±AKI Initial labs ... hemosiderin • PT/aPTT normal ... #Algorithm #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... values: WBC >100k ... values: Elevated ... TLS #diagnosis #management ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... antiphospholipid syndrome ... - Mechanical: valve ... Cirrhosis with portal ... Diagnosis #Framework #hematology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
hypersplenism and related thrombocytopenia ... and hepatorenal syndrome ... Clues to non-cirrhotic ... • Budd Chiari syndrome ... #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... old, ~10,000 new cases ... only curative treatment ... #treatment #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
- Normal coagulation ... Treat primary cause ... - APTT < 1.5 x normal ... #treatment #management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... aplastic anemia) Labs ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Drugs: - Oral ... • Nephrotic Syndrome ... from prosthetic valves ... Heparin-induced thrombocytopenia ... pathophysiology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... blood cells appear normal ... #diagnosis #hematology
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