36 results
diagnosis hematology management algorithm syndrome oncology pathophysiology causes classification polycythemia workup dermatology disease disorders erythrocytosis hemolysis nephrology pharmacology signs symptoms
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
or priapism • Lab ... values: WBC >100k ... , + lab signs of ... values: Elevated ... diagnosis #management #hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Erythrocytosis) - Differential ... Positive - Low/Normal ... Abdominal Ultrasound ... Erythrocytosis #Differential ... Algorithm #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... ±AKI Initial labs ... hemosiderin • PT/aPTT normal ... Microangiopathy #TMA #Differential ... Management #Algorithm #hematology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
1 or Type 3) — differentiate ... cytometry— GP lb ... defects of GP lb ... Platelet #disorders #hematology ... #hemepath #differential
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... • Muscular: normal ... CK, normal biopsy ... diagnosis #management #treatment ... #rheumatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
) Differential ... appreciate the value ... shock, 33% had normal ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Blood Smear ↑ abnormal ... #Hemolysis #Differential ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... Drug-induced AIHA - Abnormal ... Prosthetic heart valves ... Extravascular #Differential ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... - Mechanical: valve ... Cirrhosis with portal ... Thrombocytopenia #Differential ... Diagnosis #Framework #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Cytopenias • Cardiac valve ... flares • CRP normal ... Erythematosus #Diagnosis #Rheumatology
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