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diagnosis management oncology syndrome algorithm workup causes classification disorders lupus pathophysiology polycythemia signs sle erythrocytosis hodgkins lymphoma platelet pv systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... permanent alopecia Differential ... Cytopenias • Cardiac valve ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Erythrocytosis) - Differential ... Positive - Low/Normal ... Abdominal Ultrasound ... Chronic Chest Symptoms ... Algorithm #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... Hepatic, Portal, ... Systemic Lupus Erythematosus ... Spleen #Enlarged #Differential ... Algorithm #Causes #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... also arise in normal ... disease: B symptoms ... #NonHodgkins #comparison ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
or priapism • Lab ... values: WBC >100k ... , + lab signs of ... values: Elevated ... diagnosis #management #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
purpuric macules • Erythematous ... • Ulcerated, erythematous ... reticularis Differential ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
onset of tender erythematous ... inflammatory disease ... values at presentation ... Criteria #Diagnosis #Hematology ... #Dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... PT, aPTT(liver disease ... pylori test (GI symptoms ... bypass), LFT (liver disease ... Causes #Workup #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Nephropathy 16% - Oral ... autoantibodies #signs #symptoms ... #mimickers #differential ... #rheumatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... , Drugs, Liver Disease ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
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