33 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... Medications - Heparin ... #Deficiencies #Summary ... #table #comparison ... #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management Summary ... marrow) -dys- (abnormal ... only curative treatment ... #Management #treatment ... #hematology #oncology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Laboratory • Normal ... type 2B) • Normal ... PT/INR • Normal ... factor VIII) Treatment ... #Hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management Summary ... JAK2 mutation OR Abnormally ... concentration in the normal ... #Management #Summary ... #treatment #hematology
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... K Antagonists, Heparin ... ISNeducation #Abnormal ... APTT #prolonged #diagnosis ... #hematology #evaluation
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... hemoglobin/hemosiderin, Hepatic ... hemosiderin • PT/aPTT normal ... #Differential #Diagnosis ... Management #Algorithm #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview Normal ... Segmented Neutrophil (Normal ... shock, 33% had normal ... temperature and 21% had normal ... neutrophil #WBC #CBC #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
imaging: Normal ... • Histology: Normal-mild ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
• Muscular: normal ... CK, normal biopsy ... splenomegaly • Hepatic ... #management #treatment ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... and Management Summary ... - CRP: Usually normal ... life-threatening • Treatment ... #rheumatology