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differential sle systemic erythematosus management symptoms thrombocytopenia aflp associations autoantibodies classification dermatology dermatomyositis druginduced hellp myopathies obstetrics pregnancy summary ttphus
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SLE : systemic lupus ... ConnectiveTissueDiseases #ILD ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... • Immunologic Workup ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... - CRP: Usually normal ... • Immunologic Workup ... Erythematosus #Diagnosis ... Management #Summary #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Non-scarring alopecia, Oral ... pericarditis • Hematologic ... nephritis, Class Ill ... Erythematosus #diagnosis ... #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Elevated ESR, Normal ... muscle weakness • Normal ... uncommon 5-15% of lupus ... #differential #diagnosis ... #comparison #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... Nephropathy 16% - Oral ... Differential Diagnosis ... autoantibodies #signs ... #differential #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... , Oral ulcers, Rash ... Erythematosus #SLE #Signs ... #Symptoms #diagnosis ... #rheumatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
celiac disease, CF, IBD ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... • Pulmonary: ILD ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
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