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diagnosis treatment differential algorithm sle erythematosus nephrology acr2021 guidelines systemic arteritis nephritis classification criteria druginduced gca giantcell hematology renal signs
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... ulcers, Lupus nephritis ... - CRP: Usually normal ... #Summary #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Idiopathic • Normal ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... Usual therapeutic management ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Elevated ESR, Normal ... muscle weakness • Normal ... uncommon 5-15% of lupus ... differential #diagnosis #comparison ... #rheumatology
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
Nodosa (PAN) - Vasculitis ... Management Algorithm ... Therapy; high-dose oral ... #Management #Treatment ... Guidelines #algorithm #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... - ORAL ULCERS ... SEROSITIS - RENAL - NEUROLOGIC ... #Diagnosis #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Non-scarring alopecia, Oral ... Acute cutaneous lupus ... least 2 joints • Neurologic ... Erythematosus #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... inflammation Others: • Lupus ... - Recurrent oral ... such as systemic lupus ... differential #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Diagnosis of Lupus ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... ANCA-associated vasculitis ... Non-autoimmune rheumatologic ... flares • CRP normal ... Erythematosus #Diagnosis #Rheumatology
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