138 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... PT - Prolonged aPTT ... #Coagulation #Abnormal ... #Hematology #Diagnosis ... #Workup
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... APTT Step 1: Is ... the PT or APTT ... ISNeducation #Abnormal ... #diagnosis #hematology
Prolonged APTT - Diagnostic Algorithm

#Prolonged #APTT #PTT #abnormal #Diagnosis #Algorithm #hematology
Prolonged APTT - ... #Prolonged #APTT ... #PTT #abnormal ... Diagnosis #Algorithm #hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
INR), Prolonged PTT ... Prolonged PT (INR), Normal ... PTT, Normal PT ... , Normal PT (INR ... Algorithm #Causes #Hematology
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Approach to Elevated aPTT ... Diagnosis Algorithm aPTT ... #Elevated #aPTT ... INR #Algorithm #Hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
an inhibitor of normal ... to have 50% of normal ... PT and/or aPTT) ... Study #diagnosis #hematology ... pathophysiology #hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
/uL Initial Workup ... iron studies, PT/aPTT ... Diagnosis #Algorithm #hematology ... #workup
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Laboratory • Normal ... type 2B) • Normal ... PT/INR • Normal ... aPTT (prolonged ... Disease #Diagnosis #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
antiglobulin test, PT/aPTT ... hemosiderin • PT/aPTT ... normal • DAT ... Management #Algorithm #hematology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
- No other workup ... screening, CBC, aPTT ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology