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diagnosis differential causes algorithm classification elevatedmcv hemolysis interpretation intravascular macrocytosis management mcv nutrition oncology rheumatology workup aplastic approach b12 cirrhosis
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Algorithm - Iron deficiency ... anemia - Anemia ... and/or folate deficiency ... disorder - TSH, LFTs ... Underproduction #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Microangiopathic Hemolytic Anemias ... • Early Iron Deficiency ... #Normocytic #Anemia ... Algorithm #Causes #Hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
clotting factor deficiency ... Patient has a factor deficiency ... Study #diagnosis #hematology ... pathophysiology #hematology ... #laboratory
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
• Dietary Deficiency ... Target Cells, Normal ... WBCs - Normal ... B12 and Folate Deficiency ... Algorithm #Causes #Hematology
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
Interpretation Iron deficiency ... , ↓ Ferritin Anemia ... Ferritin Iron deficiency ... #differential #hematology ... #laboratory
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
80 fL) • Iron Deficiency ... Chronic Disease Normal ... 100 fL) • B12 Deficiency ... • Folate Deficiency ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron deficiency ... some patients) Normal ... Megaloblastic: Vitamin B12 deficiency ... , Folate deficiency ... diagnosis #causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... RBC Production - Normal ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... Algorithm #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... RBC>13 • Iron Deficiency ... Malabsorption, Dietary Deficiency ... TlBC > 18% • Anemia ... Algorithm #Causes #Hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... thrombopoietin deficiency ... - Anemia - Bone ... leads to chronic anemia ... LiverFailure #Hepatic #Hepatology
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