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diagnosis differential hematology algorithm treatment rheumatology oncology abnormal alopecia clinical hairloss hemolysis table thrombocytopenia acne classification criticalcare deficiency diffuse dress
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Blood Smear • Drugs ... Myelodysplastic Syndromes ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Causes of Erythema ... Drugs (antibiotics ... amoxicillin) Oral ... Sarcoidosis or Lofgren's syndrome ... Differential #Diagnosis #Dermatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease Normal ... Deficiency • Drugs ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... methotrexate) • Drugs ... Non-lmmune: • HELLP Syndrome ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Cytotoxic drugs ... (MDS) (normal or ... #oncology #hematology ... #diagnosis #management
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... some patients) Normal ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... old, ~10,000 new cases ... cytopenias (usually anemia ... #treatment #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Transfusion reactions, Drug-associated ... , PCH, Evans Syndrome ... Membrane Defects, Drugs ... Defects: Sickle cell anemia ... Blood Smear ↑ abnormal
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... infection) - Drugs ... #anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Drug induced ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... spotted fever • Drug ... #nonpalpable #dermatology
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