19 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... - DDX: - Infection ... Seronegative Reactive Syndrome ... - Synovium - Oral ... #diagnosis #msk
Bone Deformity / Limp - Differential Diagnosis Algorithm 
Infection
 • Septic Arthritis
 • Cortical Hypertrophy
 •
Diagnosis Algorithm Infection ... Legg-Calve-Perthes Disease Knee ... Patellofemoral Syndrome ... Deformity #Limp #MSK ... Diagnosis #Algorithm #Orthopedics
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH ... , Evans Syndrome ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... etc) - Viral: HIV ... antiphospholipid syndrome ... Cirrhosis with portal ... Diagnosis #Framework #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... symptoms - Pel-Ebstein ... involvement Differential ... oncology #diagnosis #differential ... #hematology
Ober's Test for TFL/ITB Inflammation

With the patient in the lateral position, affected side up.  The
, flexing the hip ... In a normal test ... Iliotibial #Band #Syndrome ... physicalexam #sports #msk ... #orthopedics
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Ig A vasculitis/HSP ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
arthritis ENT • Oral ... Heberden's nodes (DIP ... Bouchard's nodes (PIP ... #joint #pain #differential ... #diagnosis #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Mycoplasma, EBV, HIV ... younger pts) Differential ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... initiation • Differential ... Diagnosis: Infection ... 500 mg QD until normal ... fluid overload, PCC