41 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #MSK #Musculoskeletal ... Complications #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... Erythematosus #SLE ... Complications #pathophysiology ... #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... arthritis - (Reiter’s syndrome ... Erythematosus (SLE ... should have other symptoms ... #Differential #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... - CRP: Usually normal ... Usual therapeutic management ... rheumatology #diagnosis #management
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... #SLE #Mucocutaneous ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE ... cerebritis #diagnosis #management
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... erythematosus (SLE ... ) Signs / Symptoms ... #Pathophysiology ... Diagnosis #Signs #Symptoms
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Nephropathy 16% - Oral ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #mimickers #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... sedimentation rate + Normal ... permanent alopecia Differential ... : • Symptoms limited ... flares • CRP normal
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... erythematosus (SLE ... ), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... rheumatology #diagnosis #differential