76 results
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Erythrocytosis) - Differential ... Positive - Low/Normal ... Chronic Chest Symptoms ... Erythrocytosis #Differential ... Algorithm #Causes #Hematology
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Manifestations of Serotonin Syndrome ... • Ophthalmologic ... sounds, RUQ pain • Dermatologic ... ucsdim #Serotonin #Syndrome ... #Symptoms #spectrum
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Myelodysplastic Syndromes ... WBCs - Normal ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
reexposed to light; • Normal ... Holmes-Adie Syndrome ... Young females Differential ... Ill Palsy - abnormal ... PhysicalExam #neurology #ophthalmology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... diagnosis #management #hematology
Causes of Erythema Nodosum - Mnemonic

NO cause found in 60% of cases
Drugs (antibiotics e.g., sulfonamides, amoxicillin)
Oral
amoxicillin) Oral ... Sarcoidosis or Lofgren's syndrome ... Mnemonic #Causes #Differential ... #Diagnosis #Dermatology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... spine Signs / Symptoms ... Areflexia (loss of normal ... #MSK #pathophysiology ... #diagnosis #symptoms
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview Normal ... ) Differential ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... 500 mg QD until normal
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm
Relative Afferent Pupil Defect
 • Optic Neuritis
 • Ischemic
Pupillary Defects - Differential ... Opioids, Alcohol) Dorsal ... Midbrain (Parinaud's Syndrome ... Pupils #Defects #Differential ... Algorithm #Causes #Ophthalmology