35 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Non-Malignant • Amyloidosis ... • Gaucher's Disease ... Glycogen Storage Disease ... myelofibrosis) Inflammatory ... Algorithm #Causes #Hematology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Syphilis, Lyme disease ... , Leprosy • Inflammatory ... , Sarcoidosis, Amyloidosis ... Charcot-Marie-Tooth, Fabry's disease ... diagnosis #causes #neurology
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
(AA) → Chronic Inflammatory ... Clinical suspicion ... the extent of disease ... Clinical Manifestations ... • Circulating inflammatory
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Rheumatic fever • Amyloidosis ... syndrome - SLE Neurologic ... neuropathy - SLE, Amyloidosis ... Macroglossia - Amyloidosis ... differential #diagnosis #rheumatology
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
of T-helper & inflammatory ... cells) Clinical ... : • Disease fatal ... exertion • Neurologic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... Treatment: • Inflammatory ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... likely it will be clinically ... Drug-Induced, Inflammatory ... Bowel Disease, ... ANA #patterns #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
background of a highly inflammatory ... release of pro-inflammatory ... fever syndromes Clinical ... Fever is the main clinical ... #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (25-75%): Inflammatory ... skin injury) • Neurologic ... Behcet syndrome (Clinical ... signs #symptoms #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
(COVID-19) • Inflammatory ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology