33 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Unstable hemoglobin disorders ... myeloma Rouleaux: Chronic ... Inflammatory Diseases ... differential #diagnosis #hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
- Anemia of chronic ... of chronic kidney ... disease - Vitamin ... Probable bone marrow disorder ... Underproduction #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
: • Acute or Chronic ... Inflammatory: ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Non-Malignant • Amyloidosis ... • Gaucher's Disease ... Myeloproliferative disorders ... myelofibrosis) Inflammatory ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
RBCs on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... • RBC Membrane Disorder ... RBC Metabolism Disorder
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... hemorrhage) • Chronic ... inflammatory disorders ... Myelofibrosis (MF) • Chronic ... Diagnosis #Causes #hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Hematologic • Anemia ... Autoimmune / Inflammatory ... Obstructive Pulmonary Disease ... Neurologic • ... • Somatization Disorder
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... Iron deficiency anemia ... discoloration) • Chronic ... Systemic #Secondary #dermatology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
DiabetesB12 deficiency, Uremia ... Syphilis, Lyme disease ... , Leprosy • Inflammatory ... , Sarcoidosis, Amyloidosis ... diagnosis #causes #neurology
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Group of disorders ... amyloid A (AA) → Chronic ... Inflammatory Conditions ... Bronchiectasis, Chronic ... the extent of disease