16 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Polycythemia Vera • Chronic ... : • Acute or Chronic ... Inflammatory: ... disorders • Celiac disease ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... hemorrhage) • Chronic ... inflammatory disorders ... Myelofibrosis (MF) • Chronic ... Diagnosis #Causes #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Non-Malignant • Amyloidosis ... • Gaucher's Disease ... vera, essential thrombocytosis ... myelofibrosis) Inflammatory ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection • Lyme disease ... Dermatomyositis Erythema chronicum ... Scleroderma • Amyloidosis ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia, Chronic ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic ... Inflammatory Diseases ... differential #diagnosis #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Disorders: • Chronic ... Hypersensitivity Or Inflammatory ... Colitis and Crohn’s Disease ... Diagnosis #causes #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... Gastrointestinal inflammatory ... disease • ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Cellular efflux; thrombocytosis ... nonsteroidal anti-inflammatory ... Chronic kidney disease ... : SLE, amyloidosis ... Chronic kidney disease
Anemia of Chronic Disease - Pathophysiology
One theory to explain why "anemia of chronic disease" exists:
The inflammatory
Anemia of Chronic ... disease" exists ... : The inflammatory ... disease serves ... #disease #hematology