37 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
Membrane Disorder - Differential ... Diagnosis Algorithm ... often preceded by trauma ... MucousMembranes #dermatology ... #Differential #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... infarction, Severe trauma ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... fraction < 20% Differential ... #management #treatment ... #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Solar purpura - Trauma ... #Diagnosis #hematology ... #nonpalpable #dermatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... Management • ... #Diagnosis #Management ... #treatment #hematology ... #differential
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
usually to TEN in adults ... Nikolsky sign, the differential ... and toxic shock syndrome ... #Diagnosis #Dermatology ... Febrile #Fever #Differential
Facial Swelling - Differential Diagnosis Framework for Facial Edema

Infectious:
	• Dental abscess
	• Ludwig's angina
	• Vincent's angina
	• Cellulitis
	•
Facial Swelling - Differential ... Diagnosis Framework ... polymyositis • Adult-onset ... Preeclampsia Dermatologic ... #Diagnosis #PhysicalExam
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... Clinical Presentation ... Fever is the main clinical ... #Diagnosis #Management ... #Hematology #Rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... myelodysplastic #syndrome ... #differential # ... diagnosis #dermatology ... #oncology #clinical