38 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... hepatitis • Pulmonary ... #treatment #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... disorders • Celiac disease ... Post-op surgery • Trauma ... effect following treatment ... #Differential #Diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... infarction, Severe trauma ... #Differential #Diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
More common in adults ... Culture & GS, PCR Treatment ... : • Severe Disease ... #management #treatment ... #infectiousdiseases
Rhodococcus - Microbiology Overview

Microbiology:
 • Facultative, intracellular, nonmotile, non-spore-forming
 • Aerobic acid-fast gram-positive coccobacilli
 • Produces
Transmission (Zoonotic disease ... inoculation due to trauma ... Diagnosis Treatment ... #Microbiology #diagnosis ... #treatment #pulmonary
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... synovitis (40%) Treatment ... #AOSD #rheumatology ... #treatment
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
osteomyelitis, trauma ... necrosis, Lyme disease ... Treatment: admission ... washout • Healthy Adults ... pediatrics but NOT adults
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... 33% of healthy adults ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential