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diagnosis differential causes anemia fatigue macrocytic cell chronic daytime disorders electrophoresis elevatedmcv enlarged eosinophil eosinophilia erythrocytosis excessive hypercoagulable indications jaundice
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Differential Diagnosis Algorithm ... Sepsis • Drugs (e.g ... • Gilbert's Syndrome ... #Causes #Hepatology ... #bilirubinemia
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Differential Diagnosis Algorithm ... • Thrombus (e.g ... Non-Malignant • Amyloidosis ... Myeloproliferative disorders (eg ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Causes #Hematology
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
• Provoked (e.g ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm Insufficient Sleep • Poor Sleep Hygiene • Insomnia
Sleep Deprivation (Eg ... Shift Work) Sleep ... Neurologic Disorders (Eg ... • Medications (Eg ... • Drug Abuse (Eg
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... 1,500 cells/µL Workup ... signs or symptoms (eg ... Differential #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... : - Neuro: AMS ... hydration - Hyperkalemia ... unless worrisome EKG ... diagnosis #management #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Differential Diagnosis Algorithm ... Liver Failure • Hypercalcemia ... Neoplastic / Hematologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic Algorithm ... of substrate (e.g ... Algorithm by Dr. ... #Diagnosis #Workup ... #Hematology #Microcytic
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Differential Diagnosis Algorithm ... poisoning, OSA/OHS ... Paraneoplastic (e.g ... Differential #Diagnosis #Algorithm ... #hematology
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