47 results
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
presentation - Symptoms ... of GHB toxicity ... within 4-8h - Seizures ... hallucinations and seizure ... GHB #Toxicology #Toxicity
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
Drug-Induced Seizures ... Drug #Induced #Seizures ... Medication #Causes #Differential ... Pharmacology #Diagnosis #OTISCAMPBELL
Diagnostic Algorithm for the Patient with Seizure in the Emergency Department
Does the history suggest a seizure?
the Patient with Seizure ... history suggest a seizure ... of additional symptoms ... Characterize seizure ... Algorithm #Diagnosis #Seizure
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... 2) Presence of symptoms ... nausea, confusion, seizures ... Assessment of volume status ... Pseudohyponatremia #Differential
Beta-Blocker Overdose/toxicity:

•	Bradycardia & hypotension (most common).
•	Myocardial depression & cardiogenic shock (severe overdoses). 
•	Ventricular dysrhythmias (Common with
Beta-Blocker Overdose/toxicity ... Others (mental status ... change, seizure ... Nearly all develop symptoms ... • Delayed toxicity
Cerebral Toxoplasmosis 
- Most comrnon CNS infection in patients with AIDS 
who are not receiving appropriate
Altered mental status ... • Seizure ... pyrimethamine-induced hematologic toxicity
MOVE STUPID - Mnemonic for Altered Mental Status (Delirium)
 - Metabolic (hypercalcemia, hyponatremia)
 - Oxygen (hypoxia)
Altered Mental Status ... hypoglycemia) - Seizures ... encephalopathy #differential
Altered Mental Status - Differential Diagnosis
 • Neurologic: Stroke, Cerebral hypoxia, Cerebral hemorrhage, Seizure, Trauma, TBI,
Altered Mental Status ... - Differential ... Cerebral hemorrhage, Seizure ... Altered #Mental #Status ... #AMS #Differential
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
diabetes Key signs/symptoms ... altered mental status ... lethargy, coma, seizure
Differential Diagnosis of Syncope
First, is it syncope? History is very important for distinguishing syncope from other
Differential Diagnosis ... other causes (seizure ... events, prodromal symptoms ... their associated symptoms ... Sycope #Causes #Differential