10 results
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Acute Graft versus Host ... disease: vacuolar ... more sparse after BMT ... #disease #Pathology ... #Microscopy #Dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... workup, including BM ... • Nonmalignant hematologic ... Vasculitides, IBD, Celiac disease ... Diagnosis #Algorithm #hematology
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
- Primarily a disease ... extramedullary disease ... with limited BM ... involvement (<25%) - Most ... Lymphoma #hemepath #pathology
Burkitt-Like Lymphoma with 11q Aberration
Clinical
 • Provisional entity
 • Comprises a group of lymphomas that morphologically
, more limited disease ... without CNS or BM ... be seen in the post-transplant ... diagnosis #hemepath #pathology
Hepatosplenic T-cell lymphoma involving hepatic sinusoids.

HSTL also involves BM sinusoids and splenic red pulp cords and
also involves BM ... is present in most ... Lymphoma #HSTCL #Pathology ... #Microscopy #Oncology
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
Cranial Nerve V: • TMJ ... Gastrointestinal disease ... differentiate disease ... Oral exam • TMJ ... Otalgia #Ear #Pain #Otology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
of autoimmune disease ... - Most present ... presentation (PB, BM ... morphologic/clinical disease ... Leukemia #hemepath #pathology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
Myeloma: In this BM ... core, most plasma ... BoneMarrow #Clinical #Pathology ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... cells - Blood & BM ... • Cytopenia -> BM ... #Leukemia #Hematology ... #Oncology #Diagnosis
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
may arise from disease ... Neuromuscular junction pathology ... bind with the post-synaptic ... NeuromuscularJunctions #NMJ