22 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Insufficiency Addison's Disease ... Lymphoma Metastatic Disease ... include protein C deficiency ... Aldosterone Deficiency ... Reduced libido • Signs
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
unknown - Familial chondrocalcinosis ... in bones - Chondrocalcinosis ... Pseudogout #CPPD #Disease ... #Signs #Symptoms ... #Pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... / Symptoms: - ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
- Diagnosis Algorithm ... suspected: • Signs ... and symptoms of ... • Iron-deficiency ... #Diagnosis #Algorithm
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... storage disorder • Deficiency ... #Diagnosis #Signs ... #Symptoms
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... Symptoms: Fatigue ... quadrant discomfort Signs ... of autoimmune disease
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... rare, gestational diseases ... Signs/Symptoms: ... Pretibial myxedema #Primary ... endocrinology #pathophysiology
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis ... CPPD) Deposition Disease ... Pseudogout #CPPD #Disease ... #Signs #Symptoms ... #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... but elevated as disease