887 results
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Definition • Pathophysiology ... Anemia #diagnosis #oncology
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
#Pathophysiology ... #Oncology #Melanoma
Routes of spinal metastases from primary brain tumors

#braintumor #metastasis #spinalmetastasis #cnsmalignancy #neurooncology #oncology #pathophysiology
neurooncology #oncology ... #pathophysiology
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Syndrome (TLS) Pathophysiology ... Syndrome #TLS #Pathophysiology ... #oncology
Typhlitis - Neutropenic Enterocolitis

Pathophysiology:
 • Chemo → friable intestinal mucosa → bacterial translocation +/- perforation
Presentation:
 •
Enterocolitis Pathophysiology ... diagnosis #management #oncology
Retroviral Infections: Mechanisms of Oncogenesis
Note: A retrovirus is an RNA virus that uses reverse transcriptase to
#oncogenesis #pathophysiology ... #immunology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... management #hematology #oncology
Melanoma tumour progression (based on the Clark model)
 - Benign melanocytic nevi: controlled proliferation of normal
#Pathophysiology ... #Oncology #Melanoma
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... HEMATOLOGIC ONCOLOGIC ... STRUCTURAL ONCOLOGIC ... ) METABOLIC ONCOLOGIC ... #emergencies #oncology
Summary Table of Paraneoplastic Syndromes

#Diagnosis #Oncology #Paraneoplastic #Syndromes #Table
#Diagnosis #Oncology