42 results
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
- Osmotic diuretic ... , Loop diuretics ... Postobstructive diuresis ... Classification #Features #Diagnosis ... Comparison #Table #Nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential Diagnosis ... concentrating defect: • Diuretics ... • Osmotic diuresis ... #Causes #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... thiazide-like diuretics ... , Osmotic diuresis ... #differential #diagnosis ... #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Hypovolemic: Diuretics ... , osmotic (solute ... ) diuresis • Euvolemic ... Workup #Algorithm #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Renal losses, Diuretic ... alkalosis, Ketonuria, Osmotic ... diuresis, Cerebral ... #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
periodic paralysis Osmotic ... irrigation • Management ... Kidney stones caused ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... administration • Osmotic ... diuresis (see Polyuria ... #Nephrology #Differential ... #Causes
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Methazolamide Osmotic ... diuretics: • ... #Pharmacology #nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Loop and thiazide diuretics ... Hypokalemia - Osmotic ... diuresis - ... Post-obstructive diuresis ... Classification #Causes
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia Correction ... → Osmotic Demyelination ... 3cc/kg/h, loop diuretics ... Correction #goal #rate #management ... #nephrology