30 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Autoimmune Hemolytic Anemia ... Autoimmune Hemolytic Anemia ... Autoimmune Hemolytic Anemia ... disorder, Mycoplasma, HIV ... #hematology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... Risks factor for HIV ... peripheral blood smear, HIV ... (CVID, WAS), (neurologic ... Causes #Workup #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Pseudotumor - Infectious ... • CMV • HIV ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... • HCV, HBV Not ... #hematology #rheumatology ... #nonpalpable #dermatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Idiopathic • Infections ... - HIV • Immune ... immunodeficiency virus (HIV ... #oncology #hematology ... #diagnosis #management
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
- Differential Diagnosis ... etc) - Viral: HIV ... infiltration: malignancy, infection ... #Differential #Diagnosis ... #Framework #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... drug induced • Infections ... #Hemolytic #Anemia ... classification #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... Mycoplasma, EBV, HIV ... disease #hemolytic #anemia ... #hematology #diagnosis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... autoimmune hemolytic anemia ... conditions Diagnosis ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology