17 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... hemianopsia IGF-1 Overproduction ... #Excess #Overproduction
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... synthesis of IGF1R -> Activation ... /Symptoms: • GH ... abn lipid • GH ... GrowthHormone #GH
Sellar / Pituitary Mass - Differential Diagnosis Algorithm
Adenoma - Primary Anterior Pituitary
 - Secreting
Differential Diagnosis Algorithm ... Prolactin • GH ... Differential #Diagnosis #Algorithm
Algorithmic Approach to Hypothyroidism - Differential Diagnosis and Management Framework

Central Hypothyroidism (Secondary or tertiary) ↓TSH, ↓FT4
Algorithmic Approach ... ↓FT4 • Post-GH ... Differential #Diagnosis #algorithm
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Differential Diagnosis Algorithm ... Cushing's Disease • GH ... Differential #Diagnosis #Algorithm
Causes of Nephrolithiasis - Differential Diagnosis Algorithm
Radio-opaque - Calcium-containing - 90% of stones
Radiolucent - Non-calcium 10%
Differential Diagnosis Algorithm ... Hyperoxaluria: • Enteric overproduction ... Differential #Diagnosis #Algorithm
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Differential Diagnosis Algorithm ... Puberty Onset • GH ... Differential #Diagnosis #Algorithm
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Intake (diet) - Activation ... #differential #algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... hemophagocytosis and cytokine overproduction ... MAS #Macrophage #Activation
In July 2015 the ACC/AHA proposed and published an algorithm to help stratify cardiac arrest patients
and published an algorithm ... emergent cath lab activation ... CardiacArrest #Algorithm ... CathLab #NSTEMI #Activation