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thrombocytopenia anemia aflp algorithm obstetrics oncology table ttphus cd4 elevatedmcv extravascular framework hemolysis icl idiopathic intravascular lymphocytopenia lymphopenia macrocytic macrocytosis
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Syndrome and Acute ... (AFLP) Three syndromes ... (Hemolysis, Elevated ... AFLP #obstetrics #hematology ... #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC) - HELLP ... syndrome - ... uremic syndrome ... #differential # ... diagnosis #hematology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Three syndromes ... (Hemolysis, Elevated ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential ... Megakaryopoiesis • Aplastic ... Non-lmmune: • HELLP ... Syndrome • TTP ... #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... syndrome (MDS) ... Anemia #oncology #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
iron deficiency, hemolysis ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... #Diagnosis #Causes ... #hematology #secondary
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Pregnancy) - Low ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... antiphospholipid syndrome ... - Pregnancy: HELLP ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... isoniazid) • Antibiotics ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
chemotherapy) • Genetic syndromes ... Heme (lymphoma. aplasia ... /myelodysplasia) ... #hematology #Differential ... #Causes #lymphocytopenia
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