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hematology differential management causes oncology neurology algorithm rheumatology aplastic chronic classification leukemia mds myelodysplastic sweet acidosis activation apml atlas cancer
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential Diagnosis ... ): • Acute infection ... malignancies • Anemia ... Myelodysplastic syndrome ... #Causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Differential #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Cholecystitis - Diagnosis and Management Overview Types - Acute Calculous, Acalculous, Xanthogranulomatous (chronic) Complications - Gangrenous (most
and Management Overview ... Types - Acute ... Ileus - Mirizzi Syndrome ... - Bouveret's Syndrome ... Diagnosis Treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... transformation to acute ... Myelodysplastic #Syndrome ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Diagnosis: • Pancytopenia ... Treatment: • Consider ... (transfusions, antibiotics ... progress to MDS or acute ... #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Overview Who ... Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Malignant tumors, Acute ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... kidney disease, Acute ... Myelodysplastic syndrome ... #differential #diagnosis ... #causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... Drugs (Beta lactam antibiotics ... #hematology #anemia
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