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oncology classification mds anemia chronic cll enlarged hemeonc hodgkins lymphocytic lymphomas lymphoproliferative myelodysplasia nonhodgkin pancytopenia pathophysiology spleen splenomegaly syndrome syndromes
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Diagnosis Algorithm ... • Toxins • Aplastic ... Diagnosis #Algorithm ... #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... old, ~10,000 new cases ... transformation to acute leukemia ... #Management #treatment ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Diagnosis Algorithm ... • Rheumatic disorders ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Diagnosis Algorithm ... Spherocytosis • Acquired causes ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... hypertension and/or drug treatment ... white blood cell aplasia ... diagnosis #causes ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... Diagnosis Algorithm ... are present • Classic ... Treated Like Acute Leukemias ... pathophysiology #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Overview Who ... and petechiae Causes ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
CLL) - Summary Overview ... in adults • Disorder ... to large cell lymphoma ... #oncology #hematology ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age • 22 and 45 cases ... Out Secondary Causes ... • Anemia • Aplastic ... #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Overview Hodgkin's ... of about three cases ... (90-95% of cases ... #hematology #oncology ... #management
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