46 results
Trends in Platelet Adenosine Diphosphate P2Y12 Receptor Inhibitor Use and Adherence Among Antiplatelet-Naive Patients After Percutaneous
Adenosine Diphosphate P2Y12 ... Inhibitor Use and Adherence ... EBM #Cardiology #Adherence
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
Switching Between P2Y12 ... Inhibitors Oral P2Y12 ... Switching P2Y12 ... interactions between P2Y12 ... Prasugrel #P2Y12
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
combination with P2Y12 ... anticoagulation in a-fib P2Y12 ... - Inhibits the P2Y12
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
1500ng/mL • Non-adherence ... check therapeutic adherence ... poor therapeutic adherence
Escherichia coli Adherence and Pathogenic Patterns
EIEC - EPEC - ETEC - EHEC (STEC) - EAEC -
Escherichia coli Adherence ... Escherichia #Ecoli #adherence
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
resistance, non-adherence
Asthma GINA Guidelines 2019 
If Asthma is uncontrolled, first assess for adherence and inhaler technique -Then,
first assess for adherence ... assess patients adherence
Long-Acting Injectable (LAI) - Atypical Antipsychotics 
INVEGA TRINZA 3 MONTHS 
ARISTADA 2 MONTHS 
INVEGA 1 MONTH
SUSTENNA
Adherence to daily ... schizophrenia can make adherence
IBD - Assessment of Lack of Response (sLOR) - Differential Diagnosis
Non-inflammatory mechanisms:
 • IBS
 • Fibrostenotic
loss - Non-adherence
Clopidogrel (Plavix) and Clopidogrel Non-responders

Clopidogrel is an irreversible selective inhibitor of the platelet low-sensitivity adenosine diphosphate
diphosphate receptor: P2Y12