64 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... Diagnosis Algorithm ... Signs of anemia ... Matthew Ho, MD PhD ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Diagnosis Framework ... aciduria, Drugs (e.g ... Non-megaloblastic: Liver disease ... Matthew Ho, MD PhD ... #Diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Diagnosis Algorithm ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... Serum Sickness Hemolytic ... #Causes #Hematology
Colonic Thumbprint Sign on Abdominal XRay - Differential Diagnosis:
 • inflammatory bowel disease: UC and CD
Colonic Thumbprint Sign ... bowel disease: ... UC and CD • infection ... (e.g. pseudomembranous ... Diagnosis #radiology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
(Cold-induced symptoms ... Diagnosis: • hemolytic ... younger pts) Differential ... #hemolytic #anemia ... #hematology #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Immunosuppression (e.g ... (e.g., Hashimoto ... Diagnosis of B-Symptoms ... Malignancies (eg ... hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... (e.g. ... #Causes #Hematology
Cardiac Amyloid - Diagnosis, Signs, Symptoms and Management

Clinical Presentation
- exertional dyspnea
- peripheral edema
- exertional syncope
- peripheral
Cardiac Amyloid - Diagnosis ... , Signs, Symptoms ... despite hx HTN) EKG ... - conduction disease ... #Symptoms #Cardiology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Chronic kidney disease ... infiltration (e.g ... Marrow suppression (e.g ... Intrinsic RBC defects (e.g ... #anemia #differential