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differential anemia management rheumatology causes classification dermatology hemolytic signs agglutinin antinxp2 antinxp2dm arteritis chf cold criticalcare cryoglobulinemia cryoglobulins cutaneous dermatomyositis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... aciduria, Drugs (e.g ... Matthew Ho, MD PhD ... #MCV #Algorithm ... #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential Diagnosis ... Algorithm Signs ... Hypersplenism, Infection ... Matthew Ho, MD PhD ... #Algorithm #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... - Differential Diagnosis ... Algorithm Low ... Chronic Disease (e.g ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... HUS • DIC • Vasculitis ... • Infection ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... hemolysis, deficiency anemia ... Rheumatologic, Vasculitides ... Matthew Ho, MD PhD ... #Algorithm #hematology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
(5%): PAN > GPA ... (3%) • Infections ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... : HCV infection, ... Labs/Diagnosis: ... tissue disorder (e.g ... Cryoglobulins #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Clinical Presentation ... • Symptoms of anemia ... anemia • Cold ... #hematology #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... Diagnosis = clinical ... systemic sx + signs ... = vasculitis vs ... systemic complaints- anemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis
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