42 results
diagnosis differential management algorithm causes anemia dermatology hemolytic vasculitis oncology classification clinical disease erythematosus joint myositis neurology pain sle systemic
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
methotrexate) • Drugs Autoimmune ... CLL • APLA Alloimmune ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... . lupus, CLL, lymphoma ... idiopathic) - Autoimmune ... differential #diagnosis #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm Signs ... Hemolysis: • Autoimmune ... Hypersplenism, Infection ... Matthew Ho, MD PhD ... Diagnosis #Algorithm #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Wiskott-Aldrich syndrome ... Inflammatory and Autoimmune ... Diseases: • Systemic lupus ... deficiency Infections ... Differential #Diagnosis #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... Treatment: ... Cerebritis Induction ... CNS #neurology #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
parvovirus B19 infection ... Schönlein purpura • PAN ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
Polyarteritis Nodosa (PAN ... immunosuppressive agent (e.g ... @MithuRheum #PAN ... Vasculitis #Management #Treatment ... Guidelines #algorithm #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... thrombocythemia), Autoimmune ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
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