15 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... Diagnosis Algorithm ... Signs of anemia ... Matthew Ho, MD PhD ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Non-megaloblastic: Liver disease ... Matthew Ho, MD PhD ... Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease ... Matthew Ho, MD PhD
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
- Diagnosis Algorithm ... suspected: • Signs ... Iron-deficiency anemia ... microscopic colitis Differential ... Matthew Ho, MD PhD
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... younger pts) Differential ... chills, flank pain ... #hematology #diagnosis
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... vasculitis (5%): PAN ... vasculitis (3%) • Infections ... #semiology #signs ... pathology #lesions #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... noninflammatory Signs ... #Differential # ... Diagnosis #MSK # ... rheumatology #Monoarticular
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... mass and NO prior signs ... Differential diagnosis ... diffuse chondral disease ... #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... ), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
syndrome - SLE Neurologic ... Vasculitis (e.g., PAN ... conditions #joint #pain ... #differential # ... diagnosis #rheumatology