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hematology differential management workup causes classification disorders leukemia treatment abnormal approach calculation cancer chagas chronic cll cord crisis dermatology disease
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Loss • Acute ... Deficiency • Aplastic ... #Algorithm #Causes
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... and symptoms: ... progress to MDS or acute ... #Anemia #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... result from low blood ... #Anemia #oncology ... #hematology #diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... • Marrow Aplasia ... Normal RBCs • Acute ... #Algorithm #Causes
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... marrow failure: Aplastic ... Index > 3: • Acute ... blood loss: Trauma ... #differential #diagnosis
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... in peripheral blood ... High in acute blood ... #Algorithm #Diagnosis
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Algorithm Acute ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... #Algorithm
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
ischaemia. 2) Aplasia ... - Acute worsening ... of the baseline anaemia ... Crisis #Features #Signs ... #Symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Algorithm • Confirm ... repeat testing • Acute ... nephrolithiasis • Symptoms ... (proteinuria, RBC ... #urology #blood
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