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hematology differential management causes algorithm leukemia syndrome treatment acidosis aki approach calculation chronic cll dermatology disorders elevation emergencies erythematosus gap
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Blood Loss • Acute ... Deficiency • Aplastic ... #Classification ... #Differential #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... • Marrow Aplasia ... Normal RBCs • Acute ... Inflammation • Cancer ... #Differential #Diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... Diagnosis: • Pancytopenia ... progress to MDS or acute ... #Anemia #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... • ↓ WBC • ↓ ... #Anemia #oncology ... #hematology #diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... marrow failure: Aplastic ... infiltration (e.g. cancer ... Index > 3: • Acute ... #differential #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... transformation to acute ... treatment #hematology #oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... Cancer Related ... cyclophosphamide) #Acute ... #Oncology #Differential ... #Diagnosis #Classification
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... Leukostasis: • WBC ... Hyperuricemia • Acute ... #differential #diagnosis ... #cancer
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
for 21% of all cancers ... EBV viral load, signs ... and classification ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
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