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diagnosis differential algorithm management causes hemolytic syndrome disorders leukemia rheumatology treatment aplastic arthritis blood chronic classification cll disease hemolysis laboratory
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... #Laboratory #Testing ... #workup #diagnosis ... #hematology #hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Diagnosis Algorithm Signs ... • Extrinsic RBC ... • Intrinsic RBC ... Diagnosis #Algorithm #hematology
Leser–Trélat Sign on Physical Exam Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy. #Leser
Leser–Trélat Sign ... Physical Exam Acute ... paraneoplastic sign ... #video #skin #dermatology ... #oncology
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 Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Infectious: • Acute ... Non malignant hematologic ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Normal RBCs • Acute ... Spherocytes, RBC ... #Normocytic #Anemia ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Blood Loss • Acute ... • Anemia of Chronic ... Non-lmmune #Anemia ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... • Nonmalignant hematologic ... , deficiency anemia ... Diagnosis #Algorithm #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... hypertension • Unusual RBC ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup ... #hematology #testing
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Fatigue • Acute ... (Pancytopenia, WBC ... Lymphocytic Leukemia (CBC ... Algorithm #Causes #Hematology ... #Oncology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
INDICATIONS FOR TESTING ... evaluation or workup ... 1,500 cells/µL Workup ... organ-specific signs ... Differential #diagnosis #hematology
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