45 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Artifact (redo CBC ... Infectious: • Acute ... or Chronic Inflammatory ... disorders • Celiac disease ... Iron deficiency anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Myelodysplastic syndrome ... Malignant tumors, Acute ... Hemolytic uremic syndrome ... #differential #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
of chronic kidney ... disease, Acute ... Alcohol use, Liver disease ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
transform into a RBC ... deficiencies: Chronic ... kidney disease, ... Index > 3: • Acute ... Production #Index #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
vein: Budd-chiari syndrome ... Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... > 2 • NASH, Chronic ... injury: > 3 • Chronic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... , deficiency anemia ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... transformation to acute ... #treatment #hematology ... #oncology
Short Bowel Syndrome - Acute and Chronic Adverse Signs and Symptoms of Ileal Resection
 • Dehydration
Short Bowel Syndrome ... - Acute and Chronic ... Adverse Signs and ... • Pernicious Anemia ... Ileal #Resection #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - ACS, AKI, acute ... >100k, + lab signs ... TLS #diagnosis #management ... #hematology