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diagnosis differential algorithm rheumatology causes arthritis classification leukemia approach cll erythematosus generalized lupus lymphocytic management msk pain pruritus secondary sle
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Reactive: - Systemic ... Fatigue • Acute ... Age > 50 • Chronic ... Algorithm #Causes #Hematology ... #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Infectious: • Acute ... or Chronic Inflammatory ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Chronicity: • Acute ... rheumatic fever • Chronic ... hepatitis, herpes • Chronic ... #rheumatology # ... approach #workup
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... Spherocytes, RBC ... Algorithm #Causes #Hematology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... pericarditis • Hepatic: PBC ... Musculoskeletal: joint ... #diagnosis #signs ... symptoms #testing #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... , deficiency anemia ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... of chronic inflammation ... deficiencies: Chronic ... Index > 3: • Acute ... Production #Index #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm - Systemic ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Hyperthyroidism CBC ... #generalized #dermatology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (MCV): Average RBC ... High in acute blood ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
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