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hematology causes algorithm management rheumatology arthritis dermatology pain secondary systemic thrombocytosis approach checklist classification cll generalized joint lymphocytic msk nephrology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Diagnosis Algorithm ... Fatigue • Acute ... Age > 50 • Chronic ... #Diagnosis #Algorithm ... Causes #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Artifact (redo CBC ... Myelogenous Leukemia ... Infectious: • Acute ... Iron deficiency anemia
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... Diagnosis Algorithm ... Disorders • Acute ... (ALL) • Acute ... - Hemolytic Anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #diagnosis #workup ... #oncology #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... #Differential #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... Thrombocytosis): • Acute ... malignancies • Anemia ... myeloid leukemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... deficiencies: Chronic ... Index > 3: • Acute ... #differential # ... diagnosis #calculation
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... - Differential ... Diagnosis Framework ... leukemia Measure ... Malabsorption, Chronic
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